Xalanol Eye drops

Latanoprost 0.005% and Timolol 0.5%

1. What Xalanol® is and what it is used for?
This medicine contains two active ingredients, Latanoprost and Timolol Maleate. Latanoprost is a prostaglandin analogue. It works by increasing the drainage of aqueous humour out of the eyeball. This decreases the pressure within the eye. Timolol is a beta-blocker. This medicine block beta-receptors in various parts of the body. Blocking the beta receptors in the eye reduces the amount of aqueous humour that is produced. Timolol therefore reduces the inflow of aqueous humour into the eyeball and so decreases the pressure within the eyeball.

2. Before you take Xalanol®
Do not take this medicine and tell your doctor if:

This combination is contraindicated in hypersensitivity to any component of the preparation. Do not take this medicine if the above applies to you. If you are not sure, talk to your doctor before taking Xalanol®.

Take special care with Xalanol®
Check with your doctor before taking this medicine if:

A severe form of angina pectoris, not caused by exertion, absence of the lens of the eye (aphakia), closed angle glaucoma, diabetes, glaucoma caused by accumulation of pigment particles in the drainage channels of the eye(pigmentary glaucoma), glaucoma due to inflammation inside the eye, glaucoma due to the growth of new blood vessels over the iris, heart failure, history of allergies and severe heart disease, inherited glaucoma, low blood pressure (hypotension).

Taking other medicines
Precipitation occurs when eye drops containing thimerosal are mixed with latanoprost. If such drugs are used they should be administered with an interval of at least 5 minutes between applications. Patients receiving a beta-adrenergic blocking agent orally and Timolol should be observed for potential additive effects.

Pregnancy and breast-feeding
The safety and efficacy of this medicine have not been established in children and adolescents.

3. How to take Xalanol®
Taking this medicine

Always use Xalanol® exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

How much to take?
The usual dose is one drop into the affected eye, or eyes once daily.

If you take more Xalanol® than you should
If you have too much of this medicine, talk to your doctor straight away.

If you forget to take Xalanol®
If you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

If you stop taking Xalanol®
Do not stop taking this medicine without talking to your doctor. You should not stop taking Xalanol® just because you feel better. This is because the problem may come back or get worse again.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, Xalanol® can cause side effects, although not everybody gets them.

Headache, skin rashes, inflammation of the lining of the eye, causing pain and redness (conjunctivitis), inflammation of the eyelids (blepharitis), disorders of the front layer of the eye (cornea), change in colour of the iris (the coloured part of the eye), darkening, thickening and lengthening of the eyelashes, red eye due to excess blood supply (hyperaemia), pain in the eye and eye irritation including stinging, burning and itching.

Tell your doctor if any of the side effects gets serious or lasts longer than a few days, or if you notice any side effects not listed in this leaflet.

5. How to store Xalanol®?
Before opening the cap, keep the bottle in its box in a refrigerator (2°-8° C) protected from light. After opening, keep the bottle in its box in a cool place below 25° C. The contents should be used within one month after the dropper is opened. Keep out of reach of children.

Xalanol Eye drops Prescribing Information

Located in: Eye Care