1. When to take Ribox®?
For the symptomatic relief of osteoarthritis (OA), rheumatoid arthritis (RA), ankylosing spondylitis, and the pain and signs of inflammation associated with acute gouty arthritis.
2. How to take Ribox®
Osteoarthritis: The recommended dose is 30 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 60 mg once daily may increase efficacy.
Rheumatoid arthritis: The recommended dose is 90 mg once daily.
Acute gouty arthritis: The recommended dose is 120 mg once daily up to 8 days.
Ankylosing spondylitis: The recommended dose is 90 mg once daily. Elderly: No dosage adjustment is necessary for elderly patients.
Paediatric patients: Etoricoxib is contra-indicated in children and adolescents under 16 years of age.
3. Who should not take Ribox®?
Etoricoxib is contraindicated to hypersensitivity to the active substance or to any of the excipients. Etoricoxib also contraindicted to patients who have active peptic ulceration or active gastro-intestinal (GI) bleeding, experienced bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 (cyclooxygenase-2) inhibitors, congestive heart failure, patients with hypertension whose blood pressure is persistently elevated above 140/90mmHg and has not been adequately controlled, established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease.
4. How Ribox® works?
Etoricoxib is a COX-2 selective inhibitor which is 106.0 times more selective for COX-2 inhibition over COX-1.
5. How supplied?
Ribox® 60 tablet: Box containing 30 tablets in 3 x 10's blister strips. Each tablet contains Etoricoxib INN 60 mg. Ribox® 90 tablet: Box containing 30 tablets in 3 x 10's blister strips. Each tablet contains Etoricoxib INN 90 mg. Ribox® 120 tablet: Box containing 20 tablets in 2 x 10's blister strips. Each tablet contains Etoricoxib INN 120 mg.