1. What Flubex is and what it is used for?
Flubex is a preparation of Flucloxacillin. It acts in similar way to Penicillin by inhibiting bacterial cell wall synthesis. It is used for the treatment of confirmed or suspected staphylococcal and other Gram-positive coccal infections. Indications include pneumonia, osteomyelitis, skin and soft tissue and wound infections, infected burns, cellulitis.
2. Before you take Flubex
Do not take this medicine and tell your doctor if:
Flucloxacillin should not be given to patients with a history of hypersensitivity to beta-lactam antibiotics (eg penicillins, cephalosporins). Flucloxacillin should not be used in the eye, either conjunctivally or locally. Patients with a previous history of flucloxacillin-associated jaundice/hepatic dysfunction.
Take special care with Flubex
Check with your doctor before taking this medicine if:
Hepatitis, predominantly of a cholestatic type, has been reported (see Adverse Reactions). Jaundice may first appear several weeks after therapy. Flucloxacillin should be used with caution in patients with evidence of hepatic dysfunction. Caution should be exercised in the treatment of patients with an allergic diathesis. Dosage should be adjusted in patients with renal impairment.
Taking other medicines
Probenecid decreases the renal tubular secretion of Flucloxacillin. Concurrent use with Flucloxacillin may result in increased and prolonged blood levels of Flucloxacillin.
Pregnancy and breast-feeding
Pregnancy category B
Animal studies with FLUBEX have shown no teratogenic effects. The product has been in clinical use since 1970 and the limited number of reported cases in human pregnancy have shown no evidence of untoward effect. Flucloxacillin is excreted in breast milk in trace amounts. An alternative feeding method is recommended to avoid any possible sensitisation of the newborn.
3. How to take Flubex
Taking this medicine. Always use Flubex exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
How much to take (Dosage and Administration as short form)
For Adult: 250 to 500mg four times daily before meal (half an hour).
For Children (2-10 years): Half of adult dose; under 2 years- one fourth of adult dose.
If you take more Flubex than you should
Flucloxacillin is normally a safe drug. It is unlikely to cause any problems if you give an extra dose by mistake.
If you think your child may have had too much flucloxacillin, contact your doctor.
If you forget to take Flubex
- If you miss a dose, wait until the next normal dose. Do not give the missed dose.
- If you forget to give the dose before your child has eaten, but remember during the meal, give them the dose straight after finishing the meal.
If you stop taking Flubex
Do not stop taking this medicine without talking to your doctor. You should not stop taking Flubex just because you feel better. This is because the problem may come back or get worse again.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. Possible side effects
Side effects, as with other penicillins, are uncommon and mainly of mild and transitory in nature. Gastrointestinal upsets (e.g., nausea, diarrhoea) and skin rashes have been reported. If a skin rash occurs, treatment should be discontinued. Hepatitis and cholestatic jaundice have been rarely reported.
Tell your doctor if any of the side effects gets serious or lasts longer than a few days, or if you notice any side effects not listed in this leaflet
5. How to store Flubex?
Store in a cool and dry place, away from light.Keep out of reach of children.