Calcium Orotate

What Calorate is and what it is used for?
Calorate is the tablet preparation of Calcium Orotate 400 mg & 740mg. Calorate (Calcium Orotate) is a calcium supplement with a functional amino acid chelating ligand - orotic acid. Orotic acid assists the transport of calcium through cellular membrane structures, thus facilitating the intracellular uptake of calcium, particularly in bone. Calcium Orotate also helps in the maintenance of healthy cartilage. Calorate is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.

Before you take Calorate
Do not take this medicine and tell your doctor if:
You have incomplete or infrequent bowel movements, kidney stone, kidney disease, sarcoidosis, increased activity of the parathyroid gland, high amount of calcium in urine, high amount of calcium in the blood and extreme loss of body water.

Take special care with Calorate
Before taking calcium, precaution is needed if the patient has any allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Precaution is needed before using this product in kidney disease, kidney stones, little or no stomach acid (achlorhydria), heart disease, disease of the pancreas, a certain lung disease (sarcoidosis), difficulty absorbing nutrition from food (malabsorption syndrome).

Taking other medicines
Calcium can decrease absorption of the following drugs when taken together: biphosphonates (to treat osteoporosis), the fluoroquinolone and tetracycline classes of antibiotics, levothyroxine, phenytoin (an anticonvulsant), and tiludronate disodium (to treat Paget's disease). Thiazide-type diuretics can interact with calcium supplements, increasing the risks of hypercalcemia and hypercalciuria. Both aluminum- and magnesium-containing antacids increase urinary calcium excretion. Mineral oil and stimulant laxatives decrease calcium absorption. Glucocorticoids, such as prednisone, can cause calcium depletion and eventually osteoporosis when they are used for months. Oral contraceptives (birth control pills) as well as estrogen compounds such as Premarin, Estratest and Prem-pro reduce calcium. Anti-inflammatories such as NSAID drugs, Aspirin, Ibuprofen deplete calcium. Corticosteroids deplete calcium.

Pregnancy and breast-feeding
Women who are pregnant and breast-feeding need more calcium. Pregnancy-related high blood pressure is a common and serious risk for women and their babies, and taking supplemental forms of calcium orotate can help reduce these risks.

How to take Calorate (Administration)
Taking this medicine
Always use Calorate exactly as your doctor has told you. You should check with your doctor if you are not sure.

How much to take?
Adults: As an addition to the daily diet, 2-3 tablets are usually recommended with evening meal or as directed by health care professional. Absorption of calcium is the highest in doses less than or equal to 500 mg. So, taking more than 1,000 mg/day of calcium from supplements may be beneficial if the total amount is taken in divided doses in separate times during the day. Children: Consult your doctor before giving this or any dietary supplement to children.

If you take more Calorate than you should
If you have too much of this medicine, talk to your doctor straight away.

If you forget to take Calorate
If you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

If you stop taking Calorate
Do not stop taking this medicine without talking to your doctor. You should not stop taking Calorate just because you feel better. If you have any further questions on the use of this product, ask your doctor.

Possible side effects
Like all medicines, Calorate can cause side effects, although not everybody gets them.
Bloating and swelling in the abdomen are common side effects of calcium orotate. Loss of appetite, upset stomach, constipation, nausea, vomiting, unusual weight loss, mood changes, bone/muscle pain, headache, increased thirst/urination, weakness, unusual tiredness, formation of kidney stones may occur infrequently.

How to store Calorate?
Store in a cool and dry place, away from light. Keep out of reach of children.

Calorate Prescribing Information