Beximco Pharmaceuticals Ltd.

New product launches in 2015 (Updates as of 30th September)

Beximco Pharmaceuticals Ltd. (BPL), a leading pharmaceuticals in Bangladesh and forefront in bringing new technology and generic, has launched 15 products in 2015 across Cardiovascular, Endocrine Disorders, Antibiotics, Antiviral, Gastrointestinal, Anti-acne, and Antihistamine portfolios.

Cardiovascular

Olmesan® 10

Olmesan® 10 (olmesartan medoxomil), a prodrug, is hydrolyzed to olmesartan during absorption from the gastrointestinal tract. Olmesartan is a selective AT1 subtype angiotensin II receptor antagonist.
Olmesan® (Olmesartan Medoxomil) is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.

 

Betapro®

Bisoprolol fumarate 2.5 mg, 5 mg &10 mg tablet
Betapro® is the preparation of bisoprolol fumarate, a highly cardioselective beta1-selective adrenoceptor blocking agent, used for the management of hypertension.

Indications:

  • Treatment of stable chronic heart failure with reduced systolic left ventricular function in addition to ACE inhibitors, diuretics, and optionally cardiac glycosides.
  • Treatment of chronic, stable angina pectoris.
  • Treatment of essential hypertension.

The dose must be individualized to the needs of the patient. The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose.

 

Anti-acne

Clinacyn® T Gel

Clindamycin 1% and Tretinoin 0.025% Gel
Clinacyn® (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, is an antibiotic and retinoid combination gel product with two active ingredients. Clindamycin inhibits the activity of Propionibacterium acne as reduces the occurrence of acne. Tretinoin decreases the cohesiveness of follicular epithelial cells and increases the turn over thereby brings the comedones out.
Clinacyn® T Gel is indicated for the topical treatment of Acne vulgaris in patients 12 years of age and older.

 

Antihistamine

Duvent®

Rupatadine 10 mg tablet
Rupatadine 1mg/ml Oral Solution
Duvent® is the preparation of Rupatadine. Rupatadine is a second generation, non-sedating, long-acting histamine antagonist with selective peripheral H1 receptor blocker. Rupatadine possesses anti-allergic properties such as the inhibition of the degranulation of mast cells induced by immunological and non-immunological stimuli, and inhibition of the release of cytokines, particularly of the TNF (Tumor necrosis factor) in human mast cells and monocytes.

Duvent® is indicated for,

  • Symptomatic treatment of allergic rhinitis and urticaria.

 

Endocrine Disorders

Tibilon®

Tibolone 2.5 mg tablet
Tibolone is a synthetic estrogen-like steroid hormone which acts as an agonist of multiple type I steroid receptors and thus has weak estrogenic and progestational activities as well as some androgenic properties.

Indications:

  • Treatment of oestrogen deficiency symptoms in postmenopausal women, more than one year after menopause.
  • Prevention of osteoporosis in postmenopausal women at high risk of future fractures who are intolerant of, or contraindicated for, other medicinal products approved for the prevention of osteoporosis

 

Anti-diabetic

Traneta®

Linagliptin 5 mg tablet
Traneta® is a preparation of Linagliptin 5 mg tablet, used for the treatment of Type-2 diabetes as an adjunct to diet and exercise. It is a unique DPP-4 inhibitor which acts non-renal excretion pathway. As a result no dose adjustment is required and no regular kidney screening is required for dose adjustment decision. The recommended dose of Traneta® is 5 mg once daily. It can be taken with or without food.

 

Antifibrinolytic

Tranexil®

Tranexamic acid 500 mg Capsule
Tranexil® is an antifibrinolytic agent. It is effective to reverse the effects of streptokinase or other fibrinolytic activity.

Indication and Usage:
Haemorrhage or risk of haemorrhage in increased fibrinolysis that may occur in conditions:

  • Prostatectomy and bladder surgery
  • Menorrhagia
  • Epistaxis
  • Conisation of the cervix
  • Management of dental extraction in patients with coagulopathies
  • Ulcerative colitis
  • Haematuria
  • Gastrointestinal haemorrhage

 

Gastrointestinal

Liveric®

Ursodeoxycholic Acid 150 & 300 mg tablet
Liveric®(Ursodeoxycholic acid) is a naturally occurring bile acid found in small quantities in normal human bile. Ursodeoxycholic Acid reduces cholesterol content of biliary fluid and also to reduces the absorption of cholesterol from the gut.
Liveric® tablets are indicated for the dissolution of small to medium sized radiolucent, cholesterol-rich gall stones in patients with a functioning gall bladder and primary biliary cirrhosis.

 

Respiratory

Onriva 75 Bexicap

Indacaterol 75 mcg inhalation powder per capsule
Onriva® 75 Bexicap is a long-acting beta2-agonist indicated for long-term, once-daily maintenance bronchodilator treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
Onriva® 75 Bexicap capsules must not be swallowed as the intended effects on the lungs will not be obtained. The contents of capsules are only for oral inhalation and should only be used with the BEXIHALER device.

 

Central Nervous System

Nervalin® 25

Pregabalin 25 mg capsule
Nervalin® 25 capsule (Pregabalin 25 mg) is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, post-herpetic neuralgia & spinal cord injury. It is also indicated as adjunctive therapy for adult patients with partial onset seizures. It can be used for the management of fibromyalgia.
Nervalin® is well tolerated but a few side effects like dizziness, somnolence, dry mouth, edema, weight gain, abnormal thinking and blurred vision may occur. Pregabalin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

 

Anti-viral

Sofovir-C®

Sofosbuvir 400 mg tablet
Sofovir-C® tablet (Sofosbuvir 400 mg) is indicated for the treatment of chronic hepatitis C (CHC) infection as a component of a combination antiviral treatment regimen. Sofosbuvir efficacy has been established in subjects with HCV genotype 1, 2, 3 or 4 infections, including those with hepatocellular carcinoma. Sofovir-C®, as part of a combination therapy, has been shown to work for genotypes 1, 2, 3, and 4 in just 12 or 24 weeks, depending on genotype.

Lesovir-C®

Ledipasvir 90 mg+ Sofosbuvir 400 mg tablet
Lesovir-C® is a fixed-dose combination of ledipasvir and sofosbuvir used to treat chronic hepatitis C genotype 1 or genotype 4 infection in adults. It is the first approved regimen that does not require administration with interferon or ribavirin, two drugs also used to treat HCV infection.

 

Steroids

Bexipred® Eye Drops

Prednisolone acetate ophthalmic suspension, USP 1%
Prednisolone acetate is a glucocorticoid that has 3 to 5 times the anti-inflammatory potency of hydrocortisone. Glucocorticoids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.
Bexipred® Eye Drops is indicated for the treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe. Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and in posterior subcapsular cataract formation.

Cortiflo®

Deflazacort 6mg Tablet
Deflazacort is a corticosteroid. It works by preventing or reducing inflammation. It is used to treat a number of conditions that are characterized by excessive inflammation.

Indications
Deflazacort is used to treat a variety of inflammatory conditions including asthma, arthritis, allergic disorders and certain disorders of the skin, kidney, heart, digestive system, eyes and blood as well as some tumour-producing diseases.

 

Antibiotics

Tyclav®

Powder for suspension (100ml)

Amoxicillin / clavulanic acid 125mg/31.25mg per 5ml
Tyclav® 100 ml suspension (beta-lactam antibacterial penicillin co-formulated with a beta-lactamase inhibitor) is an antibiotic agent with a notably broad spectrum of activity against the commonly occurring bacterial pathogens in general practice and hospital. The beta-lactamase inhibitory action of clavulanate extends the spectrum of amoxicillin to embrace a wider range of organisms, including many resistant to other beta-lactam antibiotics.