Lacrison -T

Loteprednol etabonate 0.5% + Tobramycin 0.3%
Eye Drops

Lacrison®-T is the preparation of Loteprednol etabonate which is belongs to a group of medicines known as steroidal anti-inflammatory drugs and Tobramycin which is a broad spectrum antibiotic. Lacrison®-T is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.

Before you take Lacrison®-T?
Do not take this medicine and tell your doctor if:

  • you are allergic to any ingredient in Lacrison®-T drops or to similar medicines, including corticosteroids or aminoglycoside antibiotics.
  • you have a viral disease in the eye, including herpes simplex keratitis (dendritic keratitis), vaccinia, or varicella
  • you have a mycobacterial or fungal infection of the eye
  • you are breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.
Take special care with Lacrison®-T
Check with your doctor before taking this medicine if you suffer from, or have in the past suffered from:

  • Tell your doctor if you already have glaucoma
  • Tell your doctor if pain develops, or if redness, itching, or inflammation gets worse
  • See your doctor if your symptoms do not get better within 2 days. He/she may want to re-evaluate your condition
  • Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, and defects in visual acuity and fields of vision. Steroids should be used with caution in the presence of glaucoma. If this product is used for 10 days or longer, intraocular pressure should be monitored.
  • Use of corticosteroids may result in posterior subcapsular cataract formation
  • Long-term use of this medicine or other eye drops that contain steroids, may lower your ability to fight infections and may increase your chance of getting an eye infection including herpes simplex
  • Using steroid eye drops like medicine may make viral diseases of the eye worse and last longer

Taking other medicines
Some MEDICINES MAY INTERACT with Lacrison®-T Eye drops. Tell your health care provider if you are taking any other medicines, especially any of the following:
Certain diuretic medicines (eg, furosemide), cyclosporine, nonsteroidal anti-inflammatory medicines (NSAIDs) (eg, ibuprofen), or other medicines containing aminoglycoside antibiotics (eg, tobramycin, gentamicin) because the risk of their side effects may be increased by this eye drops.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine as steroids may be harmful to the baby.

3. How to take Lacrison®-T (Administration)?
Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

How much to take?

Apply 1 or 2 drops of Lacrison®-T into the conjunctival sac of the affected eye every 4 to 6 hours. During the initial 24 to 48 hours, the dosing may be increased, to every 1 to 2 hours. Frequency should be decreased gradually as warranted by improvement in clinical signs. Care should be taken not to discontinue therapy prematurely.

If you take more Lacrison®-T than you should

Putting too many drops in your eye(s) is unlikely to lead to unwanted side effects. Tell your doctor or a pharmacist.

If you forget to take Lacrison®-T

If you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose

If you stop taking Lacrison®-T

Always use this medicine exactly as your doctor has told you. Do not stop using Lacrison®-T without speaking to your doctor first. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Burning or stinging upon using Lacrison®-T Eye drops; mild itching, discomfort, or redness of the eye.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; sensitivity to light; severe or worsening pain or inflammation, redness, swelling, or discharge from the eye or eyelid; unusual tearing. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.
5. How to store?
Keep this medicine out of the sight and reach of children.
Discard the bottle 28 days after opening, even if there is solution remaining.
Do not store above 25°C (room temperature). Do not freeze.


Lacrison-®T Eye Drops Prescribing Information

Located in: Eye Care